Dynamicsof invitro acquisitionof resistancebyCandida parapsilosis to di¡erent azoles
نویسندگان
چکیده
Dynamicsof invitro acquisitionof resistancebyCandida parapsilosis to di¡erent azoles Ana Teresa Pinto e Silva, Sofia Costa-de-Oliveira, Ana Silva-Dias, Cidália Pina-Vaz & Acácio Gonçalves Rodrigues Department of Microbiology, Faculty of Medicine, University of Porto, Porto, Portugal; Cardiovascular Research and Development Unit, Porto, Portugal; Department of Microbiology, Hospital S. João, Porto, Portugal; and Burns Unit, Department of Plastic and Reconstructive Surgery, Hospital S. João, Porto, Portugal
منابع مشابه
Journal of Dental Science and Therapy Molecular Characterization of Candida parapsilosis Species Complex in Niches of the Oral Cavity in a Cohort of Patients from Argentina with Different Oral and Dental Clinical Manifestations
Candida parapsilosis is considered to be a complex of three species due to genetic heterogeneity. Currently, it is the second most isolated yeast in bloodstream infections and oral cavity sites with C. parapsilosis sensu stricto and C. metapsilosis being the species mostly recovered from oral niches in both healthy and immunecompromised patients respectively. Disparity in antifungal susceptibil...
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Background Candida parapsilosis is one of the five common strains of yeasts involved in invasive candidiasis. The expression analysis of sterol biosynthesis pathway genes, which are associated with resistance, can assist the better understanding of antifungal resistance mechanisms. Method The antifungal susceptibility of 120 clinical C. parapsilosis isolates was examined. The changes in the g...
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The in vitro activity of the azasordarin GW 471558 was compared with those of amphotericin B, flucytosine, itraconazole, and ketoconazole against 177 clinical isolates of Candida spp. GW 471558 showed potent activity against Candida albicans, Candida glabrata, and Candida tropicalis, even against isolates with decreased susceptibility to azoles. Candida krusei, Candida parapsilosis, Candida lus...
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